Dr Amy Chahal at The Centre for Medical Aesthetics

Rejuran

Polynucleotide skin treatment · quality, not volume

Rejuran works on skin quality rather than shape. It does not fill, lift or freeze anything — it aims to improve the condition of the skin itself, which is a slower and less dramatic proposition than most things marketed alongside it.

Book an assessment

Assessed before it is recommended. If it is not the right treatment for you, we will say so.

Treatment room at The Centre for Medical Aesthetics, Surry Hills

What it is, and what it is not

Rejuran uses polynucleotides — fragments derived from DNA — delivered into the skin to support repair processes and improve hydration, elasticity and overall skin condition over a course of treatments.

The important distinction is that it is not a filler. It adds no volume and changes no contours. People who arrive expecting the visible change a volumising treatment produces are usually disappointed, and that is a mismatch of expectation rather than a failure of the treatment.

What it can do is improve the quality of thin, tired, crepey skin over months. It is slow, cumulative and best judged against imaging rather than memory.

What it does and does not address

Set against the things people commonly confuse it with.

Concern Rejuran Better suited
Skin quality, crepiness, hydration Well suited
Fine lines on thin skin Helps over a course
Lost volume or hollowing Does nothing A conversation with Dr Chahal about structure
Laxity and sagging Does nothing Sofwave or Morpheus8
Pigmentation Does nothing Pico laser

If what you want is a visible change in shape, this is not the treatment and we will tell you so at assessment.

What it is used for

What to expect, realistically

  1. On the dayNumbing first. The treatment itself is quick. Expect small raised areas that settle within hours.
  2. Days 1 to 3Possible bruising and swelling. This is the part people are not always warned about, so we warn you.
  3. Weeks 4 to 12Change accumulates across a course, typically spaced a few weeks apart.
  4. Months 3 to 6Assessed against your baseline imaging. Maintenance is usually needed to hold the result.

Fees

Quoted in writing at your assessment, including the number of sessions we expect, before you commit to a course.

Consultation at The Centre for Medical Aesthetics

When we would not recommend it

If your concern is volume, contour or sagging, this will not address it and a course would disappoint you. That is a different conversation and we would rather have it first.

Active skin infection, certain medical conditions and pregnancy are reasons to postpone.

All medical procedures carry risk, and individual results vary. Suitability is determined at assessment, not on the phone.

Common questions

Is it a filler?

No. It adds no volume and does not change shape. It works on the quality of the skin itself, which is a different goal.

Does it hurt?

Numbing is used. Most people describe it as uncomfortable rather than painful, and brief.

How many sessions?

A course of three to four spaced a few weeks apart is typical, then maintenance. You will be given a number at assessment.

Will I bruise?

Possibly. Plan for a few days without an important event, particularly for the first session.

When will I see a difference?

It is gradual. Meaningful change is usually apparent by the end of a course and best judged against your baseline images.

Can it be combined with other treatments?

Often, and sequencing matters. Your assessment will set the order.

Skin quality is a slow project

Rejuran suits people who want their skin to be in better condition rather than their face to look different. If you want the second thing, say so and we will talk about what actually does it.

Choose a consultation

240 Riley St, Surry Hills · (02) 8074 1559

Reviewed by Dr Amy Chahal, Cosmetic Physician

Last reviewed 17 August 2026